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Peter A Serrano


Peter A Serrano

Hunter College, USA

Biography

Peter A Serrano received his Undergraduate degree from UCLA and his Doctorate in Biopsychology from the University of California, Berkeley. Following in the footsteps of his graduate mentors, Prof. Mark Rosenzweig (Psychology) and Prof. Edward Bennett (Biochemistry), he continues to merge these two disciplines (Psychology and Biochemistry) in his research. His current interest involves how the trafficking of PKMζ during episodes of memory is disrupted with methamphetamine treatment. His hypotheses revolve around the role of inflammation involving the upregulation of cycloxygenase-2 (COX-2). As this protein can impair the ubiquitin proteosome pathway, altering the trafficking and protein turn over of PKMζ.

Abstract

Abstract : Acute methamphetamine produces long-term deficits in hippocampal- dependent spatial learning and memory retention, decreases PKMzeta and dopamine 1 receptors (D1), and increases microglial and prostaglandin J2 expression