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Nicolas Marie


Nicolas Marie

Neuroplasticity and Therapies of Addictions, CNRS, France

Biography

During his PhD (obtained in 2003 from University Paris Descartes) Nicolas Marie worked on the cellular and molecular mechanisms (signaling, desensitization, receptor trafficking) of human delta opioid receptor regulation in the biochemistry laboratory of University Hospital Center of Caen ( France). Then, he moved to University College Cork (Ireland) as a post-doctoral fellow to work on the mechanisms of intracellular trafficking. In 2005 he joined the team of Dr. Florence as a CNRS scientist to work on preclinical research in drug (mainly cocaine and opiates) addiction using multipte approaches (cell biology, molecular and behavioral pharmacology, biochemistry).

Abstract

Abstract : Methadone blocks analgesic tolerance induced by morphine pretreatment