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Kailash N Pandey


Kailash N Pandey

Tulane University, USA

Biography

Kailash N. Pandey is a Professor and Vice Chair in the Department of Physiology, Tulane University, School of Medicine. He received M.Sc. from Kanpur University, India, and Ph.D. in 1979 from University of Kentucky, Lexington. He completed postdoctoral at Vanderbilt University and subsequently was promoted to faculty. In 1990, he moved to Medical college of Georgia and in 1997 joined Tulane University, School of Medicine. The research in his laboratory has focused on atrial natriuretic peptide (ANP) and guanylyl cyclase/natriuretic peptide receptor-A (GC-A/NPRA)-mediated regulation of blood pressure and cardiovascular homeostasis. His laboratory deduced the amino acid sequence of murine GC-A/NPRA and genomic sequence of Npr1 (coding for GC-A/NPRA). In collaboration with Professor Oliver Smithies (University of North Carolina), they established genetically altered mouse models with varying Npr1 gene copies numbers (0-, 1-, 2-, 3-, and 4-copy) to conduct molecular physiological studies of hypertension and cardiovascular diseases. He has published 106 research articles, 21 book chapters, 221 abstracts, Special Guest Editorship of the Journal of Peptides, and Editorship of one book. He has trained more than 40 postdoctoral fellows and students and his research has been continuously funded by grants from NIH and AHA and held AHA Established Investigatorship Award. Currently, he is on the editorial board of six Journals and served as the reviewer on several NIH and AHA study sections.

Abstract

Abstract : Regulation of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Gene Expression and Signaling: Interactive Roles of Histone Modifications and Transcription Factors