Marija Knezevic-PoganÄev
Child and Youth Health Care Institute of Vojvodina, Serbia
Title: Ictal EEG activity in West syndrome
Biography
Biography: Marija Knezevic-PoganÄev
Abstract
Epileptic Spasms (ES) in West Syndrome (WS) are a specific type of attack with a unique clinical and Electroencephalographic (EEG) pattern. Reanalyzing only EEGs for 25 followed for at least 10 years in Child and Youth Health Care Institute of Vojvodina symmetrical spasms were present in both cryptogenic and at symptomatic WS, while the asymmetric spasms and focal epileptic spasms characteristics indicate brain lesion. Positive vertex slow waves EEG pattern were present in both groups. Fast activity resembling a spindle corresponds with absence while electro-decremental activity presents postictal. Lateralized slow activity is significantly more common among symptomatic WS with a poor prognosis and structural brain lesions. Consistent fast beta activity EEG ictal lateralization is significantly more common among children who show resistance to initial therapy. Fat low voltaged activity often progress with the development of epileptic encephalopathies, indicating cortical dysfunction. Although independent of WS etiology, hypsarrhythmia that persists during ES series indicates a good prognosis.