Neuropharmacology

Biography

Biography: Gajender Singh Ranga

Abstract

Human carcinoembryonic antigen (CEA) is a tumour marker used to diagnose various malignanacies. Striking similarties have been reported between process of tumourigenesis and atherosclerosis. CEA has been reported a useful biomarker for diagnosis of acute coronary syndrome whose pathogenic mechanism is is rupture of atherosclerotic plaque. Although, same pathogenic mechanism leads to ischemic stroke, the role of CEA for diagnosis of acute ischemic has not been evaluated so far. We are the first one to conduct this pilot study and found CEA to be a very useful biomarker for diagnosis of acute ischemic stroke as well. Although ,CT scan and MRI have taken big step forward towards diagnosis of acute ischemic stroke, early diagnosis is still a major challenge. Moreover , these facilities are not available at every centre and sometimes their results may be false negetive. In these circumstances and for early diagnosis of acute ischemic stroke CEA has been found to be a very useful biomarkes by us. Our results are encouraging, as for diagnosis of acute coronory syndrome several useful diagnostic markers are available but for early diagnosis of acute ischemic stroke only few have been reported and they are not very robust and not widely used. Our stringent exclusion criteria further make our study result remarkable.The results of our study will be discussed in detail.