Neuropharmacology

Biography

Biography: Bouchra Oneib

Abstract

Depressive disorders are within the most prevalent mental disease worldwide. We know that 40–50% of depressed patients are detected in primary health care, and 20% receive adequate treatment. Early diagnosis can improve well-being of patients, ensure a better antidepressant response and reduce the risk of recurrence and suicide. The objective of the study is to determine the prevalence and the impact life of depressive disorders in primary health care and its associated factors. We conducted a cross-sectional study with 351 participants selected from Moroccan primary care facilities, aged above 18 years without chronic somatic or psychiatric disease. The participants answered a questionnaire that included demographic characteristics, the Mini International Neuropsychiatric Interview for major depressive episode (MDE), dysthymic disorder and the Global Assessment of Functioning (GAF). The prevalence of depressive disorders in the sample was 13.7%, that of MDE was 9.1%, while dysthymic disorder was 4.3%, and the prevalence of depression over a lifetime was 17.7%. Analysis of GAF scores showed an average of 76.2 ± 24, a lower score was significantly found among patients with current MDE (P = 0.001), dysthymic subjects (P = 0.001) and those who suffer from recurrent MDE (P = 0.001). Depressive disorders in univariate analysis were associated with: Female gender odds ratio (OR) 2.1 (1.09-4.3), unemployment OR 0.4 (0.2-0.9), and childbearing age OR 3.5 (1.5-8). The high prevalence of depressive disorders and the alteration of the quality of life among primary health care patients in Morocco suggest the importance of identifying and treating this population.