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10th International Conference on Neuropharmacology and Neuropharmaceuticals, will be organized around the theme “Recent Innovations in Neuropharmacological Studies”
Neuropharma 2017 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Neuropharma 2017
Submit your abstract to any of the mentioned tracks.
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Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology, behavioral and molecular. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
- Track 1-1Structure/Function
- Track 1-2Physiology and signaling
- Track 1-3Physiological disorders
- Track 1-4Neurodegenerative diseases
- Track 1-5Novel therapeutic approaches and potential applications
Molecular neuropharmacology involves the study of neurons and agonist, Competitive antagonist and Non-competitive antagonist, receptors on neurons for developing new drugs that will treat neurological disorders of neurodegenerative diseases. Neurogenesis and repair refers to the growth and development of neuron. Neurons never function in isolation; they are organized into ensembles or circuits that process kinds of information which are referred as neuronal circuits.
The GABA inhibitory neurotransmitter and serotonin neurotransmitter present in the central nervous system of mature vertebrate interacts with GABA receptor and 5HT receptor respectively. GABAA receptors are modulated by the channel of 5HT receptors through activation of various proteins. There are about 14 5HT receptor subtypes identified from last 20 years which are now researched for their significance in various disorders and treatments. Synaptopathy is a progressively popular term used to define main features of psychiatric and neurodegenerative diseases. It infers that brain diseases are resulted from disruption of synaptic structure and function.
- Track 2-1Neurogenesis and repair
- Track 2-2Studies on neuronal circuits
- Track 2-3GABA , 5HT receptors and its neuronal development
- Track 2-4Synopathy in neurodegenerative diseases and ageing
- Track 2-5Manipulation of ion channels by drugs
Clinical neuropharmacology covers a wide range of neurologic and a few psychiatric disorders, with an emphasis on clinical relevance. Unlike most neuropharmacology texts, it is organized according to specific clinical conditions rather than type of Neuropharmacological agent. It is the science that studies the features, properties, responses and uses of drugs mainly their therapeutic effect in humans along with toxicology, pharmacodynamics and pharmacokinetics. It also includes drug abuse, pain and hypothalamic releasing factors. Most frequently occurring neurologic disorders are included with a heavy emphasis on movement disorders.
- Track 3-1Clinical neuropharmacology of drug abuse
- Track 3-2Clinical neuropharmacology and therapeutics
- Track 3-3Clinical neuropharmacology of pain
Psychopharmacology is the learning of the effects of medication on the psyche (psychology), observing changed behaviors and how molecular events are manifest in a measurable behavioural form. Neurogenesis and repair deal with other aspects on the indications for medications prescribed to address psychiatric and behavioural problems, that are associated with, including antipsychotic, anxiolytic and anticonvulsant medications, acquired brain injury and psychopharmacology drugs and their interaction with neurotransmitters also include mood stabilizers and treatments prescribed for disorders of attention.
The treatments may cause side effects such as induction of the metabolic syndrome, type II diabetes related to the medications prescribed for management of psychiatric and behavioural disorders and disturbances. The effectiveness of the drugs can be increased by prescriber’s knowledge over emotional and interpersonal issues of the patient i.e. psychology of psychopharmacology. Schizophrenia is such a disorder which affects the thinking and acting ability of a person caused by viral infection, genetically or by immune disorder.
- Track 4-1Preclinical psychopharmacology
- Track 4-2Clinical and translational psychopharmacology
- Track 4-3Psychopharmacology drugs and their interaction with neurotransmitters
- Track 4-4Dose response relation in psychiatric medications
- Track 4-5Effect of androgenic anabolic steroids on psychosis
- Track 4-6Schizophrenia and its dependence on brain chemistry and structure
- Track 4-7Psychology of psychopharmacology
- Track 4-8Molecular and synaptic mechanisms
Neurochemistry is the specific study of neurochemicals, including neurotransmitters and other molecules that include psych pharmaceuticals, neuropeptides, or gastro transmitters that influence the function of neurons. It also deals how these neurochemicals influence the network of neural operation. The studies include micro-macro connection between the analysis of organic compounds active in the nervous system and neural processes such as cortical plasticity, neurogenesis and neural differentiation, synapses, autism and intellectual disability, interneuron coordination, interaction of drugs and its effect on summation and transmission process and advances in astrocyte-neuron interactions in health. Astrocyte dysfunction results into neurodegenerative diseases, stroke, epilepsy, migraine and neuro inflammatory diseases.
- Track 5-1Dopamine
- Track 5-2Neuropeptides
- Track 5-3Monoamines
- Track 5-4Human synapses
- Track 5-5Autism and intellectual disability
- Track 5-6Advances in astrocyte-neuron interactions in health and disease
- Track 5-7Interneurons: coordinators of neuronal synchrony
- Track 5-8Drug interaction in various stages in neurotransmitters
- Track 5-9Target drugs in summation and co-transmission
- Track 5-10Serotonin
It is the study of drug dependence and how drug addiction affects the human mind, Anxiety and Autism, Measuring neural activity in Drug abuse, Alcoholism- tolerance to and physical dependence, and properties are mediated through its effects on dopamine neurons in the mesolimbic reward pathway, which connects the ventral tegmental area to the nucleus acumens, Post-traumatic stress disorder and borderline personality disorder, clinical depression and enhanced treatments.
- Track 6-1Anxiety and Autism
- Track 6-2Measuring neural activity in drug abuse
- Track 6-3Alcoholism- tolerance to and physical dependence
- Track 6-4Post-traumatic stress disorder and borderline personality disorder
- Track 6-5Clinical depression and enhanced treatments
Neurotransmitters are endogenous, special messenger chemicals that enable neurotransmission. They transmit signals across a chemical synapse, such as a neuromuscular junction, from one neuron (nerve cell) to another "target" neuron, muscle cell, or gland cell. Neurotransmitters are released from synaptic vesicles in synapses into the synaptic cleft, where they are received by receptors on the target cells. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available from the diet and only require a small number of biosynthetic steps for conversion.
They can also affect mood, sleep, concentration, weight, and can cause adverse symptoms when they are out of balance. These are of two types: Inhibitory and Excitatory. Acetylcholine, Glutamine and GABA are some of these neurotransmitters.
- Track 7-1Mechanism
- Track 7-2Optical techniques and advances
- Track 7-3Trans cranial magnetic stimulation
- Track 7-4Novel trans-synaptic tracing approaches
- Track 7-5Modern neurocircuitry analysis
- Track 7-6Neurotechnology
- Track 7-7Neurotransmitter imbalance
- Track 7-8Elimination of neurotransmitters
- Track 7-9Precursors
- Track 7-10Agonists and antagonists drug effects
- Track 7-11Brain neurotransmitter system
- Track 7-12Excitatory and inhibitory actions
- Track 7-13Neuromodulation and implant
It deals with a branch of immunology concerned with the interactions between immunological and nervous system functions also associated autoimmune diseases. Cortical system involves the study of mapping neural systems associated in the processing of emotion, and it focuses on the cortical components of the process of recognizing facial expressions. Encephalitis is acute inflammation of the brain resulting from a viral infection or an autoimmune disease. Transverse myelitis is a pathogenically heterogeneous inflammatory disorder in which spinal cord is affected. Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability.
Blood brain barrier is a selectively permeable membrane that separates the blood in the brain from other extracellular fluids. Meningitis, epilepsy, cerebral edema, multiple sclerosis etc. are various diseases associated with it. The children of age group 1 to 14 are more prone to cancer, out of which 18% is the case of brain tumor. In the first three decades of life, central nervous system has emerged as one of the three vulnerable leading sites for cancer mortality. Cerebral lymphoma is the most rapidly increasing brain tumor.
- Track 8-1Cortical systems and their complexity
- Track 8-2Transverse myelitis spectrum disorders and prognosis
- Track 8-3Epilepsy and epileptic seizures
- Track 8-4Brain Injury and Stroke
- Track 8-5Huntington’s disease and linkage with cognitive & psychiatric disorders
- Track 8-6Epigenetics and its role in neuroimmunopharmacology
- Track 8-7Immuno-pathogenesis of brain tumor
- Track 8-8Blood Brain Barrier and associated disorders
- Track 8-9Clinical neuropharmacology of hypothalamic releasing factors
It is the study of interactions between the nervous system and the endocrine system, also biological features of the cells involved and their communications. Most Important aspects of neuroendocrinology are insulin receptor and hypothalamic programming; stress, coping and interactions, neuro-endocrine-immune symphony, pituitary structure and hormone secretion. Alzheimer's is a type of dementia that causes problems with memory, thinking and behaviour. Symptoms usually develop slowly and become severe enough to interfere with daily tasks. Amyloid plaques are also found in the brain of Alzheimer patients. Neurocognitive effects associated with therapeutic drugs and animal cognition and behaviour - Fear and aversive learning and memory.
- Track 9-1Insulin receptor and hypothalamic programming
- Track 9-2Environmental effects associated with disease
- Track 9-3Animal cognition and behaviour- Fear and aversive learning and memory
- Track 9-4Neurocognitive effects associated with therapeutic drugs
- Track 9-5Symptoms, causes and diagnostics
- Track 9-6Drug designing and therapeutics
- Track 9-7Alzheimer’s disease and dementia
- Track 9-8Pituitary structure and hormone secretion- New Insights
- Track 9-9Stress, coping and interactions
- Track 9-10Role of amyloid protein in Alzheimer
It is a progressive and chronic disorder, caused by death or malfunctioning of neurons, genetic mutation leading to decreased level of dopamine secretion. It can cause neuropsychiatric disturbances that range from mild to severe. This includes disorders of speech, cognition, mood, behaviour, and thought. Mostly it is idiopathic (having no specific known cause) type. However, a small proportion of cases are known genetic factors. Other factors have been associated with the risk of developing PD, but no causal relationships have been proven. There is no cure for Parkinson's disease, but medications, surgery, and multidisciplinary management can provide relief from the symptoms.
- Track 10-1Impact of genetic mutations
- Track 10-2Interdependent disorders such as neurodegenerative disorders and ageing
- Track 10-3Anxiety, depression and stress level in Parkinson’s
- Track 10-4Approaches involved in diagnostics
- Track 10-5Drug designing and therapeutics
It includes the social, legal and ethical consequences of advances in neuroscience. It is the amalgamation of neuroscience with ethical thoughts. The ethics of neurocognitive includes brain interventions and imagining, neurological treatments and consciousness disorders. Neuroethics encompasses a wide range of issues, which can only be sampled here. Some have close ties to traditional biomedical ethics, in that different versions of these issues can arise in connection with organ systems other than the brain. In contrast, many neuroethical issues are at least partly novel and this accounts for some of the intellectual fascination of neuroethics. These relatively newer issues force us to think about the relation between mind and brain and its ethical implications.
- Track 11-1Neurological disorders and implications for society
- Track 11-2Brain interventions and brain imaging
- Track 11-3Neuroethics of neurological treatments and management
- Track 11-4Neuroethics associated with different stages of consciousness and related disorders
Neuropharmacology is an emerging field of science, rising exponentially with the understanding of nervous system and its related disorders, drugs and treatments. The major area of research includes mechanisms of novel drugs, neuro stem cell therapy, immunoglobulin therapy, gene therapy in neuronal disorders and neural engineering. Ultrasound systems comprise 29% of the global medical imaging systems market. X-ray systems are next, with a 24% share. Positron emission tomography has seen growth but it is the smallest segment. The X-ray market is growing well due to the introduction of digital technology.
- Track 12-1Neuroprotection
- Track 12-2Neurovirology
- Track 12-3Neuro-radiology
- Track 12-4Neurotoxicity
- Track 12-5Neurogenetics
- Track 12-6Neuro-Ophthalmology
- Track 12-7Neuroscience
- Track 12-8Novel drugs and their mechanisms
- Track 12-9Gene therapy in neurological disorders
- Track 12-10Neural engineering
Neurons are known as excitable cells because on its surface membrane there are an abundance of proteins known as ion-channels that allow small charged particles to pass in and out of the cell. The structure of the neuron allows chemical information to be received by its dendrites, propagated through the perikaryon (cell body) and down its axon, and eventually passing on to other neurons through its axon terminal.
Neurotransmitter/receptor interactions in the field of neuropharmacology are extremely important because many drugs that are developed today have to do with disrupting this binding process.
- Track 13-1Interactions with organic compounds
- Track 13-2Alcohol and neurotransmitter interactions
- Track 13-3Interactions between Neurochemical and Environmental Influences
The great advances made in the department of pharmacology have been placed in this session. A few new ones have been introduced but the most important additions have come chiefly from chemist laboratory. Chemists have gradually discovered methods to modify that composition by the introduction of new elements, and thus render these active principles more suitable and more effective for therapeutic employment.
- Track 14-1Novel therapeutic approaches in epilepsy
- Track 14-2Advances in pharmacological therapy of Parkinson’s disease
- Track 14-3Neuropharmacology of emesis
- Track 14-4Current therapeutic strategy in Alzheimer’s disease
- Track 14-5Advances in neuropharmacological rehabilitation for brain dysfunction
- Track 14-6New technologies in Medicine
- Track 14-7Varicose vein treatment
Case studies are extremely useful records of the clinical practices of a profession. They are a record of clinical interactions which help us to frame questions for more rigorously designed clinical studies. Case studies also provide valuable teaching material, demonstrating both classical and unusual presentations which may challenge the practitioner. Analysing a case study requires you to practice applying your knowledge and your thinking skills to a real situation. To learn from a case study analysis you will be “analysing, applying knowledge, reasoning and drawing conclusions.”